How Cannabinoids and Terpenes Work Together: A Patient’s Guide to Florida Medical Marijuana

Florida legalized medical marijuana in June 2014 for low‑THC, high‑CBD products (like Charlotte’s Web) and expanded access under Amendment 2, passed on November 8, 2016. Patients with qualifying conditions and a Florida Medical Marijuana Use Registry card can now access various cannabis products—including smoking, vaping, and edibles—under state regulations.

What Are Cannabinoids?

Cannabinoids are compounds produced by the cannabis plant that interact with the body’s endocannabinoid system (ECS)—regulating pain, mood, appetite, inflammation, sleep, and more. Over 80 cannabinoids exist naturally, but the two most prominent are:

Florida patients may find products labeled by CBD-to-THC ratio, or options like isolated CBD, balanced formulations, or THC‑dominant cultivars.

What Are Terpenes?

Terpenes are aromatic compounds found in cannabis (and many other plants). They influence the smell, taste, and possibly some therapeutic effects of different marijuana strains.

More than 100 cannabis terpenes have been identified. The most common include:

The Entourage Effect: How Cannabinoids & Terpenes Work Together

The entourage effect refers to the synergy between cannabinoids, terpenes, and other compounds—working together to enhance therapeutic outcomes. In practice, terpenes may modulate how THC or CBD are absorbed and processed by the body and influence their effects indirectly (e.g. through GABA or olfactory receptors).

For example, a strain high in THC and rich in linalool may feel more relaxing and less jittery than a THC-only product. Similarly, adding pinene might help counteract memory impairment or paranoia sometimes linked to high THC.

Tips for Florida Patients Choosing Products

  1. Read the lab label — Florida-certified products often include terpene profiles and cannabinoid concentrations, helping you identify strains with desirable effects.
  2. Talk to your physician or budtender — Ask about specific cannabinoid ratios and terpene profiles tailored to your needs (e.g. anxiety, pain, sleep).
  3. Start low and go slow — Especially with THC; begin with a low dose and note how a strain’s terpene profile impacts you.
  4. Keep a journal — Log strain, ratio, terpene content, method of administration, and effects. Apps like Strainprint can help track responses over time.
  5. Minimize heat exposure when preserving terpenes — Terpenes are volatile and degrade easily. Vaporizing at lower temperatures or choosing extracts like ice‑water hash or live resin helps preserve their effects.

Strain Types: Indica, Sativa, Hybrids… and Chemovars

Historically, cannabis was classified as Indica (typically relaxing) or Sativa (energizing), with Hybrids blending traits. However, experts now encourage focusing on chemovars—the plant’s chemical profile (including terpenes and cannabinoids)—because the same strain name can differ widely in composition.

Further Reading & Resources

Summary

Welcome to your medical cannabis journey in Florida—armed with terpene and cannabinoid knowledge, you’ll be better equipped to choose products that align with your goals and well‑being.